Date Posted: Oct 10, 2018
Application Deadline: Open Until Filled
- Location: South San Francisco, CA
- Job Number: 7053664
- Posting Date: Oct 10, 2018
- Application Deadline:
Open Until Filled
Inaugural postdoctoral position at MyoKardia investigating the implications of various myofilament mutations in both normal and pathological cardiac development. MyoKardia is a clinical-stage biopharmaceutical company that seeks to improve patientâ€™s lives by both pioneering a precision medicine approach to discover targeted therapies for the treatment of serious/rare cardiovascular disease, as well as by increasing the scientific understanding of normal and pathological cardiac function.
As such, a joint research group between MyoKardia and its academic founders is seeking a highly motivated postdoctoral candidate with a background in cardiovascular genetics, biochemistry, physiology, and/or structural biology to join the organization. The work, expected to encompass a two-year tenure, intends to leverage novel large animal models of inherited sarcomere-driven diseases, the Sarcomeric Human Cardiomyopathy Registry (SHaRe), and protein-specific sarcomere functional modulators to further the understanding of the role that sarcomere proteins/mutations play in healthy and pathological cardiac development.
ESSENTIAL DUTIES AND RESPONSIBILITIES:
â€¢ Independently manage project/experiments, ranging from design and execution to reporting
â€¢ Be an active contributor to MyoKardiaâ€™s scientific process
â€¢ Active contributor to MyoKardiaâ€™s peer-reviewed dissemination (e.g., publications, conferences, etc.)
â€¢ Build/facilitate a strong academic/collaborative environment, both intra- and extra-murally.
PhD and/or MD with demonstrable laboratory experience in cardiovascular genetics, biochemistry, physiology, and/or structural biology
â€¢ Strong record of accomplishment and publications
â€¢ Demonstrable ex vivo toolset, with (ideally) hands-on in vivo experience, particularly in large animals
â€¢ Effective communication skills
â€¢ A high degree of independence
â€¢ Ability to work as a member of a collaborative team