Date Posted: Nov 22, 2018
Our group has recently shown that polyploid giant cancer cells (PGCCs), which have been generally considered non-viable due to their inability to execute mitosis, can grow and divide via amitosis. These giant cancer cells may function as the most primitive cancer stem cells via dedifferentiation into blastomere-like stem cells (Zhang et al, Oncogene, 33(1):116-28, 2014; Niu et al, Oncogenesis 5(12):e281, 2016; Niu et al, Oncogene 36(34):4887-4900, 2017); Liu J, Dualistic Origin of Human Tumors, Seminars in Cancer Biology, 2018. Thus, our study links the cancer development to the cleavage stage embryogenesis, the very beginning of life. These unexpected findings provide a novel paradigm on cancer biology and therapy.
We are interested in studying the underlying mechanisms of polyploid giant cancer stem cells in therapeutic resistance. A post-doctoral fellow position is immediately available for recent PhD or MD/PhD graduate in biomedical science and cancer research. The candidate must have a track record of successful Ph.D. study and have documented publications in internationally peer-reviewed scientific journals) and great scientific English language skill. In addition to superb lab skills, the candidate must have demonstrated ability to conduct independent scientific investigations. A strong background in cell biology, cancer biology, molecular biology, or pathology is required. The position will be open until filled.
The University of Texas M.D. Anderson Cancer is #1 ranked cancer center in the US and offers rich environment for research and professional development. If interested, please send a cover letter, CV, name and contact information of at least three references to: Jinsong Liu, MD/PhD, Professor, Department of Pathology, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030-4095. E-mail: email@example.com. Tel/Fax: (713) 745-1102/(713) 563-1848
M. D. Anderson Cancer Center is an equal opportunity employer and does not discriminate on basis of race, color, national origin, gender, sexual orientation, age, religion, disability or veteran status except where such distinction is required by law. All positions at The University of Texas M. D. Anderson Cancer Center are security sensitive and subject to examination of criminal history record information. Smoke-free and drug-free environment.