- Yale School of Medicine
- Location: NEW HAVEN, CT
- Job Number: 7062501
- Posting Date: Nov 26, 2019
- Application Deadline: Open Until Filled
Job DescriptionPostdoctoral positions are available to study Wnt and GPCR signaling in inflammation and immuno-oncology in the Department of Pharmacology, Yale University School of Medicine, New Haven, CT.
Both Wnt proteins and G protein coupled receptors (GPCRs) play important roles in a wide range of biological and pathophysiological processes. We have been using various biochemical, molecular and cell biological, structural biological, genomic, proteomic, large scale RNAi and CRISPR/Kas9 screening, and transgenic and gene targeting approaches to study these pathways. We have made important contributions to characterization of Wnt signaling mechanisms (Mol. Cell 7, 801; Nat Genet. 37, 945; Science 321, 1350; JCB, 200, 419; Nature Comm. 6,8205), a novel tumor immune evasive mechanism (Nat. Med. doi:10.1038/nm.4496), cell migration mechanisms and their roles in inflammatory and vascular diseases (Nature Medicine 22: 1033-42;; Cell Report 14,734; Dve. Cell 27,215; Nature Cell Biology 4, 686; Dev. Cell 21, 1038, Immunity 33, 340, JCI 118, 195, S, Nat. Cell Biol. 7, 399, Cell 114, 215, Science 287, 1046). We continue working along these lines with increased emphasis on tumor immunity and inflammation.
Competitive salary and excellent work environment are offered. Self-motivated individuals with an advanced degree in any area of biomedical sciences and specially those who are skilled in immunobiology are encouraged to apply. Please send CV and names of three references to:
Dianqing (Dan) Wu, Ph.D.
Vascular Biology and Therapeutics
Department of Pharmacology
Yale University School of Medicine
P.O. Box 208089, Rm-337E
10 Amistad Street
New Haven, Connecticut 06520-8089