- Lawrence Berkeley National Laboratory
- Location: Berkeley, CA
- Job Number: 7063480 (Ref #: 90571)
- Posting Date: Feb 12, 2020
- Application Deadline: Open Until Filled
Job DescriptionPostdoctoral Researcher - 89267
Organization: MB-Molecular Biophys & Integ Bio
Berkeley Lab’s Molecular Biophysics and Integrated Bioimaging Division (https://biosciences.lbl.gov/divisions/mbib/) has an opening for a Postdoctoral Researcher. In this role you will develop new computational methods for the structure determination and refinement of protein structures using the PHENIX software system. Primary duties and responsibilities will include development and implementation of numerical methods and new computational protocols, including the application of machine learning methods. The Phenix software is used worldwide for the determination of atomic structures using X-ray and neutron crystallography and cryo-electron microscopy. The software is developed as part of an international collaboration supported by the National Institutes of Health and the Phenix Industrial Consortium.
What You Will Do:
• Development and implementation of computational algorithms for structure determination using crystallography and cryo-electron microscopy including: improved methods for the optimization of models and automated detection of model heterogeneity.
• Application of machine learning methods to problems in crystallography and cryo-electron microscopy.
• Develop and test new components of the PHENIX software system in collaboration with others
• Document software developments.
• Collaborate with other researchers in the PHENIX program.
• Interact with P.I.s, other postdocs, scientists and external collaborators involved in the PHENIX project.
• Publication of research results in scientific journals and presentation of results at scientific meetings.
Additional Responsibilities as needed:
• Participate in workshop and tutorials to educate researchers in the use of Phenix
• Actively participate in writing progress reports
What is Required:
• Ph.D. in computational crystallography, computational cryo-electron microscopy, computational biology, bioinformatics, computational chemistry or a related field
• Demonstrated experience in developing computational algorithms for solving problems
• Demonstrated experience with computational methods development
• Publications in macromolecular crystallography, cryo-electron microscopy or closely related fields
• Familiarity with Python, C++ and other software development tools
• Good programming and mathematical skills
• Strong interpersonal skills and the ability to work in a team environment
Additional Desired Qualifications:
• Familiarity with macromolecular structure or computational chemistry.
• Experience with the practical aspects of crystallography and/or cryo-electron microscopy.
The posting shall remain open until the position is filled.
• This is a full time, 2 year postdoctoral appointment with the possibility of renewal based upon satisfactory job performance, continuing availability of funds and ongoing operational needs. You must have less than 3 years paid postdoctoral experience. Salary for Postdoctoral positions depends on years of experience post-degree.
• Full-time, M-F, exempt (monthly paid) from overtime pay.
• This position is represented by a union for collective bargaining purposes.
• Salary will be predetermined based on postdoctoral step rates.
• This position may be subject to a background check. Any convictions will be evaluated to determine if they directly relate to the responsibilities and requirements of the position. Having a conviction history will not automatically disqualify an applicant from being considered for employment.
• Work will be primarily performed at: Lawrence Berkeley National Lab, 1 Cyclotron Road, Berkeley, CA.
How To Apply
Apply directly online at http://188.8.131.52/counter.php?id=176235 and follow the on-line instructions to complete the application process.
Berkeley Lab (LBNL, http://www.lbl.gov/) addresses the world’s most urgent scientific challenges by advancing sustainable energy, protecting human health, creating new materials, and revealing the origin and fate of the universe. Founded in 1931, Berkeley Lab’s scientific expertise has been recognized with 13 Nobel prizes. The University of California manages Berkeley Lab for the U.S. Department of Energy’s Office of Science.
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