- The University of Texas MD Anderson Cancer Center
- Location: Houston, TX
- Job Number: 7069436
- Posting Date: Sep 3, 2020
- Application Deadline: Open Until Filled
Job DescriptionA Postdoctoral position is available in the Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States. This position reports to Dr. Linghua Wang.
We are seeking a talented and highly motivated Postdoctoral Fellow to work on the cancer single cell profiling projects. The primary research focus is: to apply innovative bioinformatics approaches to dissect tumor ecosystem and better understand tumor-immune co-evolution and therapy response. In particular, to profile in-depth the cellular & functional heterogeneity, lineage plasticity and evolutionary dynamics of tumor cells, and cells of the tumor immune microenvironment (TIME).
The Postdoctoral Fellow will carry out integrative analysis of the multi-platform single cell sequencing (e.g., scRNA/TCR/BCR/ATAC-seq) and immunogenomic datasets generated on specimens from patients and pre-clinical models, to comprehensively characterize the tumor ecosystem and elucidate mechnisms of resistance, and identify predictive/prognostic biomarkers and potential targets, that could be harnessed to design rational therapeutic interventions. The postdoctoral will have great opportunities to collaborate with diverse groups of physician scientists, immunologists, and computational biologists at MD Anderson Cancer Center and will be mentored by Dr. Linghua Wang, MD, PhD, PI of the Computational Biology Lab at Department of Genomic Medicine.
Individuals with a PhD degree in computational biology, bioinformatics, data science or a related field are encouraged to apply. A strong computational background, proficiency in R and at least one additional scripting language (e.g. Python, Perl) and knowledge in biostatistics are required. Experience working with single cell sequencing data analysis and high-performance computing environment (Unix/Linux) is highly preferred. A good understanding of cancer biology, immunology, cell biology, and molecular biology is also preferred. Proven track record of publications, excellent spoken and written communication skills are required.
Stipend support will follow the NIH Kirschstein-NRSA stipend levels level for the appropriate PGY.
Interested applicants should send a Cover Letter specifying past research experience/skills/accomplishments, a Curriculum Vitae and the contact information of three (3) Referees to Dr. Linghua Wang at Lwang22@mdanderson.org with the subject line entitled “Postdoctoral Fellow - Application – Applicant’s Name”.
It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law.
Diversity and inclusion at MD Anderson are not just important; they are essential. We take an expansive view of diversity, considering differences in race, ethnicity, sexual orientation, gender and religious beliefs, as well as communication styles, thought, skill and ambition. We constantly examine our culture to create an inclusive working environment that effectively attracts, retains, develops and utilizes the skills and talents of all employees. Our Diversity Council develops strategies to attract and retain superior talent and enhance workforce diversity and inclusion. We also offer multiple diversity training programs to our employees.
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