Evaluating mechanism-based therapeutic strategies in adult T-cell leukemia/lymphoma
- Albert Einstein College of Medicince
- Location: New York City, NY
- Job Number: 7069718
- Posting Date: Sep 11, 2020
- Application Deadline: Open Until Filled
Job DescriptionCONTACT: Dr. B. Hilda Ye
Department of Cell Biology
A POSTDOCTORAL FELLOWSHIP is available in Dr. B. Hilda Ye’s laboratory at the Albert Einstein College of Medicine in New York to investigate mechanism-based therapeutic strategies in adult T-cell leukemia/lymphoma (ATLL). ATLL is an extremely aggressive disease of malignant CD4+ T cells and is a major health problem affecting the immigrant population in the Bronx. In collaboration with clinicians at the Montefiore Medical Center, the Ye laboratory previously showed that compared to ATLL diagnosed in Japan, North American ATLL has unique driver oncogenes as well as transcriptomic and immunologic features. Unique resources including patient-derived cell lines and PDX models have been developed to decipher the function of several molecular pathways targeted by recurrent somatic mutations in the ATLL patients. Related publications are linked to the laboratory homepage at: https://www.einstein.yu.edu/faculty/7901/b-hilda-ye/
Motivated and experienced postdoc researchers are welcome to apply. You should have a PhD in immunology, molecular biology, cancer biology, biomedicine or a closely related area. You should have broad knowledge of cancer biology and/or molecular immunology with high level skills in cell culture, molecular assays, Western blotting, flow cytometry and microscopy. Experience with in vivo animal models would be beneficial. Ability to work independently and communicate effectively, creativity, high motivation and a strong work ethic are important. Curriculum vitae with a description of research experience and contact information for three references should be sent to: firstname.lastname@example.org. Subject: ATLL PD application.
The Department of Cell Biology has a strong core of postdoctoral fellows and graduate students, working in diverse areas of cancer biology, cell biology, development, and gene expression regulation. The Department is highly interactive with a longstanding tradition to support career development of trainees. There are a variety of scientific and social interaction venues including weekly work-in-progress seminars, biweekly journal clubs, and numerous outside speaker seminars.
The Albert Einstein College of Medicine (Einstein) is one of the nation’s premier institutions for basic research and clinical investigation with 300+ research laboratories funded by more than $200 million from the National Institutes of Health. It is also one of America’s Best Mid-sized Employers rated by Forbes in 2019. There are 264 PhD students, including 106 in the combined MD/PhD programs, and ~300 postdoctoral fellows at Einstein. https://www.einstein.yu.edu/research/belfer-institute/
Albert Einstein College of Medicine is an Equal Opportunity Employer.