- The University of Texas M. D. Anderson Cancer Center
- Location: Houston, TX
- Job Number: 7073764
- Posting Date: Jan 6, 2021
- Application Deadline: Mar 6, 2021
Job DescriptionPostdoctoral position at the nexus of immunology and neurology available in the lab of Dr. Michael A. Curran at the University of Texas MD Anderson Cancer Center. Dr. Curran was the first to study and report the combination of CTLA-4 and PD-1 blockade which remains the most effective clinical immunotherapy. The Curran lab studies mechanisms of immune resistance in “cold” cancers (prostate, pancreatic, glioblastoma), in particular focused on tumor hypoxia and oxygen metabolism, as well as on novel approaches to modulation of the tumor myeloid stroma. Application of this knowledge to addressing underlying causes of neurodegeneration in models of Alzheimer’s disease has become a new focus within the lab. We have achieved success pursuing a novel immune therapy focused on removal of neurotoxic aggregates from the CNS. This work is funded by both a philanthropic award and grant, as well as by a dedicated NIH grant. Prior fellows hold tenured academic professorships, scientist positions in industry, and senior positions in patient-focused immune monitoring centers.
Successful candidates will lead a project to develop a myeloid-based adoptive cell therapy for the treatment of neurodegenerative disease. Candidates must have a recent Ph.D. degree in a related field along with lead-author publications, excellent communication skills, and the ability to work independently within a research team. Candidates who pursue an independent career path are highly preferred. Expertise in immunology, neurology/neurodegeneration, and/or viral vector based cell engineering is also desirable. We will provide a competitive salary at or exceeding the NIH postdoctoral stipend level, excellent benefits, and one-on-one mentoring and coaching for a successful research career.
Diversity and inclusion at MD Anderson are not just important; they are essential. We take an expansive view of diversity, considering differences in race, ethnicity, sexual orientation, gender and religious beliefs, as well as communication styles, thought, skill and ambition. We constantly examine our culture to create an inclusive working environment that effectively attracts, retains, develops and utilizes the skills and talents of all employees. Our Diversity Council develops strategies to attract and retain superior talent and enhance workforce diversity and inclusion. We also offer multiple diversity training programs to our employees.