About City of Hope

City of Hope is an independent biomedical research and treatment organization for cancer, diabetes and other life-threatening diseases.

Founded in 1913, City of Hope is a leader in bone marrow transplantation and immunotherapy such as CAR T cell therapy. City of Hope’s translational research and personalized treatment protocols advance care throughout the world. Human synthetic insulin, monoclonal antibodies and numerous breakthrough cancer drugs are based on technology developed at the institution.  AccessHope™, a subsidiary launched in 2019 serves employers and their health care partners by providing access to City of Hope’s specialized cancer expertise.

A National Cancer Institute-designated comprehensive cancer center and a founding member of the National Comprehensive Cancer Network, City of Hope is ranked among the nation’s “Best Hospitals” in cancer by U.S. News & World Report and received Magnet Recognition from the American Nurses Credentialing Center. Its main campus is located near Los Angeles, with additional locations throughout Southern California and in Arizona.

City of Hope’s commitment to Diversity, Equity and Inclusion

We believe diversity, equity and inclusion is key in serving our mission to provide compassionate patient care, drive innovative discovery, and advance vital education focused on eliminating cancer and diabetes in all of our communities.  Our commitment to Diversity, Equity and Inclusion ensures we bring the full range of skills, perspectives, cultural backgrounds and experiences to our work -- and that our teams align with the people we serve in order to build trust and understanding.  We are dedicated to fostering a community that embraces diversity - in ideas, backgrounds and perspectives; this is reflected in our work and represented in our people.

Position Summary

A Postdoctoral Fellowship opportunity is immediately available for the highly motivated individual in the laboratory of Dr. ZJ Sun at Beckman Research Institute of City of Hope, one of a prestigious group of NCI-designated Comprehensive Cancer Centers.

The Sun laboratory examines stem cells and stem cell niches in prostate development and tumorigenesis using “cutting-edge” and unbiased analytic tools and unique and innovative genetically engineered mouse models. The Postdoctoral Fellow will join a highly productive lab to directly work on the novel and ongoing projects to uncover cell signaling pathways, and related gene-expression and genomic and epigenetic alterations that regulate the prostatic epithelial-stromal interactions in development and tumor development and progression.

Key Responsibilities include:

• The successful applicant will investigate steroid hormone action, transcriptional control, and cell signaling in development and tumorigenesis.
• The Fellow will develop and use novel and advanced biological approaches, and genetically engineered mouse models to uncover gene-expression and genomic and epigenetic alterations in cancer initiating cells in order to understand mechanisms underlying tumor initiation, progression, and metastasis.

Basic education, experience and skills required for consideration:

• Ph.D. or M.D/Ph.D. degree in Cancer Biology, Molecular Biology, Genetics, Biochemistry, Cell Biology, or a related field.
• A proven track record of creativity and productivity.
• Highly self-motivated, strong desire to learn, and have excellent communication skills. 
• Previous experience with mouse models of human diseases, cancer biology, molecular biology, or genetics is highly desired, but not required.

Additional Information:

As a condition of employment, City of Hope requires staff to comply with all state and federal vaccination mandates. 

• For more information about Dr. Zijie Sun’s lab, please visit here.

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer.  All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

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