Postdoctoral Associate (Computational Biology)
- Texas A&M University
- Location: College Station, TX
- Job Number: 7081624
- Posting Date: Jul 26, 2021
- Application Deadline: Open Until Filled
Job DescriptionComputational biology postdoctoral positions are available in the Singh laboratory at Department of Molecular and Cellular Medicine, Texas A&M University Health Science Center. The laboratory applies and develop computational, and molecular approaches to understand transcriptional regulation. We are an integrative computational and experimental laboratory within the Department of Molecular and Cellular Medicine at Texas A&M University (TAMU) with an affiliation with the Department of Computer Science and Engineering, the Center for Statistical Bioinformatics (Department of Statistics), and the Department of Biomedical Engineering at TAMU. The primary focus of our group is to utilize diverse, high-throughput functional assays and perturbations to uncover mechanisms of transcriptional and co-transcriptional regulation in normal and diseased states. We combine the strengths of computational methods and molecular assays to dissect the functional regulatory programs in mammalian cells. We have established multidisciplinary collaborations with researchers at Dana Farber Cancer Institute, Baylor College of Medicine, and Texas Children’s Hospital.
Qualifications: Recent PhDs in one or more of the following areas: Computational biology, Computer Science, Statistics. The candidate should have a strong track record of productivity, as evidenced by first-authored publications in peer-reviewed scientific journals.
The ideal candidate(s) will have a track record of applying innovative strategies to tackle important biologic problems, together with the communication and interpersonal skills required to make a positive contribution to a thriving intellectual environment.
The candidates are expected to have a strong work ethic, excellent organizational and critical thinking abilities.
• Review of applications will begin immediately. Applications will be considered on a rolling basis.
• Please send your CV, relevant publications, and list of three referee to Dr. Singh isingh[at]tamu[dot]edu
Also include a cover letter of research interests, motivation, and experience. Briefly describe how the past/on-going work in the Singh laboratory aligns with your background and interests.
• 1. Widespread intronic polyadenylation diversifies immune cell transcriptomes
Singh I, Lee S, Sperling A, Samur MK, Tai Y, Fulciniti M, Munshi N, Mayr C, Leslie C
Nature Communications 9: 1716 (2018)
• 2. Widespread intronic polyadenylation inactivates tumor suppressor genes in leukemia
[Lee S*, Singh I*], Lee S, Tisdale S, Abdel-Wahab O, Leslie C, Mayr C [*Co-first authors]
Nature 561, 127–131 (2018)
• 3. Chromatin landscapes reveal developmentally encoded transcriptional states that define glioblastoma
[Mack SC*, Singh I*, Wang X*], … Lin CY, Rich JN [*Co-first authors]
Journal of Experimental Medicine, 216 (5), 1071 (2019)