Postdoctoral Fellow: Cancer Biology - Molecular mechanisms underpinning brain tumor development and glia functions
- The University of Texas M. D. Anderson Cancer Center
- Location: Houston, TX
- Job Number: 7081703
- Posting Date: Jul 29, 2021
- Application Deadline: Open Until Filled
Job DescriptionThe Jian Hu laboratory at MD Anderson Cancer Center is seeking outstanding and motivated postdoctoral candidates to expand our work on molecular mechanisms underpinning brain tumor development and glia functions (Hu J., et al., Cell 2012; Shingu T., et al., Nature Genetics 2017; Zhou X., et al., JCI 2020, Ren J., et al., JEM 2021, Shin S., et al., Nature Communications 2021, Zhou X., eLife 2021). We are particularly interested in strengthening three aspects of our research. The first is to decipher the mechanisms of how glioma stem cells (GSCs) manage to sustain their self-renewal capacity in the sub-optimal environment outside the niches, particularly during the process of invasion and migration. The second is to fill the knowledge gap of how glioma associated microglia/macrophages (GAMs) are converted from the antitumor to pro-tumor state and develop rational immunotherapeutic interventions to reverse immune-suppressive, tumor-promoting polarization of GAMs. Lastly, we are looking for new therapeutic approaches for demyelinating diseases such as multiple sclerosis and chemotherapy-induced neurological defects (chemo-brain).
Qualified candidates should have strong background in one or more of the following areas: neuroscience, cancer biology, neuroimmunology, metabolism, genetics, or biochemistry. We are only interested in the candidates who are committed to ask fundamentally important questions and are fearless in trying novel approaches. A track record of excellent first author publication during PhD training is essential. The pay scale follows NIH guidelines ($53,760 for fresh PhD with adjustment for more senior candidates).
MD Anderson is the number one cancer center in cancer care in the United States by the U.S. News and World Report’s “America’s Best Hospitals” survey. It ranks 1st in the number of awarded grants from National Cancer Institute. It offers active graduate and postdoctoral training programs and the unmatched scientific environment of the Texas Medical Center, the world’s largest biomedical center. MD Anderson is an equal opportunity/affirmative action employer. Houston is the 4th largest city in the United States with relatively low living cost and no state or city income tax.
The interested candidates should send a CV to email@example.com.
Jian Hu, Ph. D.
Department of Cancer Biology
Brain Tumor Center
Program of Cancer Biology
Program of Neuroscience
The University of Texas Graduate School of Biomedical Science
The University of Texas MD Anderson Cancer Center
1515 Holcombe Blvd
Houston, TX 77030
It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html