Postdoctoral Researcher; Postdoc
- Howard University College of Medicine
- Location: Washington, DC
- Job Number: 7085821
- Posting Date: Sep 21, 2021
- Application Deadline: Open Until Filled
Job DescriptionImpact of Gbx2 on neural crest cells during neuronal, craniofacial, and cardiovascular development
For a 1-year Postdoctoral position, I am seeking candidates with experience in mouse developmental research. The researcher will assist with the execution of the project “Impact of Gbx2 on neural crest cells during neuronal, craniofacial, and cardiovascular development” and will commit 40 hours per week to the project.
My lab (www.HeadHeartEvoDevo.com) studies head and heart muscle evolution, development, and pathology in vertebrates, currently with a focus on mouse models. This project is in collaboration with the University of the District of Columbia (UDC), where the PI is interested in the observed abnormalities in brain and cranial nerve development in Gbx2neo mutant mice. These mice are hypomorphs, meaning they show less severe abnormalities than the Gbx2-/- mice, which have known CNS and cardiac abnormalities. For the Neo mutants, little is known regarding their craniofacial and cardiac development and how dosage effect influences pathology in these mice. This is of importance as human syndromes with Gbx2 mutations demonstrate dosage dependent variations in their phenotypes. Our research will therefore contribute to basic science (understanding of neural crest developmental regulations) as well as to medical research (how different genotypes manifest in phenotypes).
APPLICATION: Applicants should upload a single PDF file that includes a cover letter (not more than 2 pages), a comprehensive curriculum vitae, research interests (not more than 1 page), and the names and contact information for two (2) references.
Position Description: Candidates should have a Ph.D. degree or equivalent and MUST possess familiarity in mouse breeding & handling as well as genotyping and (whole mount) in-situ hybridizations. All other methods can easily be learned. The successful candidate will be working in a dynamic academic environment. Duties will include mainly mouse embryo collection, fixation, storage, cataloging specimens, preparing solutions, performing experiments (histological staining, dissections, in-situ hybridization (ISH), etc.), analyzing and documenting immunohistochemistry data for all specimens; and contributing to writing of manuscript(s).
Rank and salary: The successful applicant will hold a full-time academic appointment in the Department of Anatomy. Salary is dependent upon the applicant's qualifications (max. $55.000).
Howard University is a private, federally chartered historically black university in Washington, D.C. There are abundant opportunities for collaborations within the College of Medicine and at nearby institutions (NIH, FDA, USDA). Howard University is an equal opportunity/affirmative action employer of minorities, females, individuals with disabilities and protected veterans and is a drug and tobacco free workplace.
Department of Anatomy
Washington,District of Columbia