Date Posted: Oct 4, 2021
Application Deadline: Open Until Filled
The Department of Dermatology at the University of Miami, Miller School of Medicine, has an exciting opportunity for a Full-time Postdoctoral Associate. The Post-Doctoral Associate will be responsible for performing research activities and experiments in the laboratory of Dr. Barbara Bedogni, on several aspects of cancer biology with a focus on melanoma. Several projects are ongoing in the laboratory including: 1) deciphering the role of the tumor microenvironment, specifically of immune responses triggered by the tumor; 2) understanding the role of Notch signaling in melanoma growth and progression; 3) understanding the role of metalloproteinases in DNA repair processes. The main models used in the laboratory include a vast array of cancer cell lines, human tumor tissues and mouse models. Projects will entail manipulation of gene expression using both RNAi and CRISPR/cas9 in conjunction with cell culture, biochemical and in vivo assays (orthotopic, xenograft and transgenic mouse models). The ideal candidate should be highly motivated, have a PhD or PhD/MD degree, a strong background in metabolism and cancer metabolism, molecular biology, cell biology, mouse genetics, big data mining and analysis, and have published in internationally recognized journals. For this position, an expertise in metabolism, cancer metabolism and big data mining and analysis, is a plus. The incumbent will assist the Principal Investigator and ensure that all experiments are appropriately conducted following the policies and procedures of the University of Miami. This position will require advance knowledge and capability to exercise independent judgment when carrying out research activities and performing non-routine and complex laboratory projects.