Postdoctoral Associate - Molecular & Human Genetics - Lupski Lab (90002278)
- Baylor College of Medicine
- Location: Houston, TX
- Job Number: 7088895 (Ref #: 9360-en_US)
- Posting Date: Nov 11, 2021
- Application Deadline: Open Until Filled
Job Description
Summary
Postdoctoral Associate will be working on project "STRUCTURAL VARIATION IN NEUROLOGICAL DISEASE". Performing array screening and breakpoint mapping of de novo CNVs in multiple de novo CNVs cases to extensively characterize breakpoint junction regions in term of their genomic architecture, and common features. Postdoc will perform genomic studies on chromosome abnormalities including marker chromosomes and inversions, and will analyze WES/WGS data of multiple de novo CNVs cases. Postdoc will identify mutations in proteins that can play a role in the initiation and selection of a CNV Mutator phenotype. Postdoc will also use WGS data to identify mutational signatures of replicative repair mechanisms in regions of chromothripsis/ Chromoanasynthesis-like events. Once an underlying mutation and an associated SNV signature are identified, postdoc will work on functionally studying the mechanistic pathway.
Job Duties
- Plans, directs and conducts specialized and advanced research experiments.
- Evaluates and analyzes data.
- Establishes new research protocols and procedures.
- Summarizes research findings and publish results in research journals.
- Responsible for laboratory operations.
- Supervises research staff.
Minimum Qualifications
- MD or Ph.D. in Basic Science, Health Science, or a related field.
Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.
9360
CA; PD
Baylor College of Medicine fosters diversity among its students, trainees, faculty and staff as a prerequisite to accomplishing our institutional mission, and setting standards for excellence in training healthcare providers and biomedical scientists, promoting scientific innovation, and providing patient-centered care. - Diversity, respect, and inclusiveness create an environment that is conducive to academic excellence, and strengthens our institution by increasing talent, encouraging creativity, and ensuring a broader perspective. - Diversity helps position Baylor to reduce disparities in health and healthcare access and to better address the needs of the community we serve. - Baylor is committed to recruiting and retaining outstanding students, trainees, faculty and staff from diverse backgrounds by providing a welcoming, supportive learning environment for all members of the Baylor community.
