Highly motivated individuals with a PhD or MD/PhD in relevant area are encouraged to apply. This training position, under the direct supervision of a Cleveland Clinic Principal Investigator will provide practical training and experience in a research setting. This position is appointed through the Lerner Research Institute. The successful applicant will be able to demonstrate a commitment to research, a collaborative work ethic and strong communication skills, both written and verbal. This program is expected to be completed within 5 years.

Principal Investigator: Kurt Runge, PhD

Lerner Research Institute Department: Inflammation and Immunity

Lab Research Topics:

• Telomeres in Schizosaccharomyces pombe
• DNA damage checkpoint suppression by telomeres
• Pef1, S. pombe ortholog of human cdk5
• Vitamin K-dependent protein carboxylation
• For more information about the lab’s research, please visit: https://www.lerner.ccf.org/immuno/runge/ or contact Dr. Runge at rungek@ccf.org

Responsibilities:

• Independent project design with the goal of data generation, analysis, interpretation and manuscript preparation
• This position is to study S. pombe telomeres
• ChIP, proteomics, Southern blotting, molecular genetics
• Study telomere suppression of DNA damage checkpoints
• Isolate nanobodies from yeast expression library

Education:

• PhD or MD/PhD required

Languages:

• English Proficiency proof required for candidates arriving on J-1, J-2, or F1 + OPT visa status

Work Experience:

• Previous experience in a research or academic setting.  Graduate student experience meets this requirement.
• Scientific writing experience

Additional Preferred Qualities:

• PhD is preferred
• Strong interest in basic science
• Expertise in molecular biology, biochemistry, cytology
• Yeast experience not required
• See PubMed ID: 29784772

Personal Protective Equipment:

• PPE per institutional requirements; may vary by laboratory

Preferred Application Materials:

• Cover letter
• CV
• Contact information for 3 references

Keywords: Postdoc, Research, LRI, DNA damage checkpoint suppression, Telomere formation, Schizosaccharomyces pombe, Proteomics, Proximity labeling