Postdoctoral Scientist - Pierson Lab - Regenerative Medicine Institute
- Cedars-Sinai Medical Center Regenerative Medicine Institute
- Location: Los Angeles, CA
- Job Number: 7091120 (Ref #: HRC0498020C)
- Posting Date: Dec 28, 2021
- Application Deadline: Open Until Filled
Job DescriptionThe Pierson Laboratory at Cedars-Sinai is looking for a Postdoctoral Fellow to start within the next few months!
Currently looking for a self-starting motivated post-doctoral fellow for immediate opening for research using IPSC modeling to study rare pediatric neurogenetic disorders. Projects include neuro-degenerative (storage disorders) and neurodevelopment (corticogenesis) etiologies and are ongoing & generating data! Research experience in a wet lab is a requirement.
The Pierson Laboratory is devoted to understanding the pathological mechanisms involved in rare and undiagnosed pediatric neurogenetic disorders. Tyler Mark Pierson, MD, PhD, has extensive experience in the phenotyping and diagnosing of rare neurogenetic disorders using modern genomic technologies. Dr. Pierson did a clinical fellowship at NINDS/NIH in the Neurogenetics Branch at the National Institutes of Health (NIH) and was a member of the Undiagnosed Diseases Program at the NIH. In addition to directing his laboratory, Dr. Pierson is also the director of the Pediatric Neurogenetics Clinic of Cedars-Sinai and the pediatric lead of the Cedars-Sinai Center for the Undiagnosed Patient.
The research goal of the Pierson Laboratory is to extend these diagnostic elements by using patient-derived induced pluripotent stem cells to understand the disease mechanisms associated with these rare pediatric neurogenetic disorders and to explore stem cell-based therapies for the delivery of therapeutic drugs, small molecules and proteins. The Pierson Lab is also involved in confirming neurogenetic diagnoses in known, but rare, neurogenetic disorders, as well as developing research to link rare presentations of neurogenetic disorders with new genes and causes.
To learn more, please visit: Pierson Research Lab | Cedars-Sinai https://www.cedars-sinai.edu/research/labs/pierson.html
The incumbent should have an interest in the basic science of induced pluripotent stem cells, neurogenetic disorders, drug screening, and gene therapy. Interest in gene regulation and lysosomal disorders are an added plus. Working independently, but in close cooperation and in consultation with the Principal Investigator and other Research Scientists, the Research Postdoctoral Fellow will perform routine and complex laboratory procedures throughout their training period. The incumbent may develop, adapt, and implement new research techniques and protocols and will analyze and interpret data. They will participate in publications and presentations as author or co-author and they may assist in the preparation of grant proposals but are not responsible for generating grant funds.
Primary Job Duties And Responsibilities
Designs and performs experiments.
Will keep appropriate experimental records and documentation and analyze the results with the Principal Investigator.
Analyzes, interprets, summarizes and compiles data.
Performs routine and complex laboratory procedures throughout training period.
Operates and maintains equipment and instruments.
Participation in laboratory meetings, keeping a lab notebook, performing calculations, tabulating data, summarizing methods and results of related experiments and general lab maintenance will be required.
The individual will be expected to function efficiently and cooperatively with a team of faculty, research associates, technicians and students.
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