Neuroinflammation in Neurodegenerative Diseases
- University of Texas Health Science Center at Houston
- Location: Houston, TX
- Job Number: 7092278
- Posting Date: Jan 14, 2022
- Application Deadline: Open Until Filled
Job DescriptionThe Cao laboratory is interested in studying the biology of neuroinflammation and related pathogenic events associated with neurodegenerative diseases. Increasingly, neuroinflammatory signals and microglial responses are critically implicated in AD and other neurodegenerative diseases. We are keen to illuminate the fundamental principles that govern the neuroinflammatory phenomena in driving AD and brain aging (check our recent publications J. Clin. Invest. 130:1912 (2020); Front Neurosci 14:577744 (2020); BioRiv 2021.11.01.466525(2021)).
Establishing a brand new presence at UTH, we are looking for an enthusiastic candidate to join a spirited group. The focus of the immediate project is to elucidate the mechanisms of neuroinflammation and to identify the key pathways and factors involved in AD by examining various CNS cells and analyzing mouse disease models. Additional projects will investigate cellular elements that modify glial functions in the aging brain and/or under the context of AD pathogenesis. Other areas of our research interest include devising strategies to target AD-relevant inflammatory and pathogenic mediators.
Candidates with training in neuroscience, molecular biology, immunology, pathology, or related disciplines are welcome. Motivated individuals with expertise in cell biology, biochemistry, immunological assays, and in vivo disease modeling are preferred. Previous experience with microscopy, bioinformatics, or stereology is a plus.