Postdoctoral Postion in Blood Brain Barrier Research
- The University of British Columbia
- Location: Vancouver , Canada
- Job Number: 7100060
- Posting Date: May 12, 2022
- Application Deadline: Open Until Filled
Job DescriptionKeywords: Endothelial cell biology, lipoprotein metabolism, cerebrovascular physiology, induced pluripotent stem cells, tissue engineering, molecular biology, bioinformatics
The Wellington Laboratory at The University of British Columbia is seeking an outstanding and self-motivated postdoctoral candidate with research accomplishments and interest in understanding the brain-heart relationship. We have a long-standing interest in the role of lipoproteins on the vascular contributions to dementia, with a particular focus on apolipoprotein E in Alzheimer’s Disease. We are seeking a postdoctoral fellow for a fully funded postdoctoral position to investigate how peripheral and brain apoE affects vascular functions relevant to Alzheimer’s Disease using traditional and advanced in vitro models of the blood brain barrier and engineered cerebral vessels. Broad objectives include characterizing the response of endothelial cell to pericyte-derived, astrocyte-derived, and peripheral apoE particles, using RNA-seq, barrier integrity and Abeta clearance as outcomes. The Wellington lab is supported by grants from the Heart and Stroke Foundation of Canada, Canadian Institutes of Health, National Institutes of Health, BrightFocus Foundation, Cure Alzheimer Fund, Weston Brain Institute and the USA Department of Defence. Please see the Wellington Lab homepage for more information. https://pathology.ubc.ca/faculty/cheryl-wellington/
This position requires a doctoral degree (PhD or MD) in cell biology, neuroscience, physiology, biochemistry, or other relevant areas of biomedical sciences. All applicants must have peer-reviewed publications in internationally recognized journals showcasing achievements in cell biology, lipoprotein metabolism, cerebrovascular physiology, induced pluripotent stem cells, tissue engineering, transcriptomics, or bioinformatics. Superior oral and written communication skills are highly desired.
The salary range for this position is approximately $60,000 CAD/year. Start date is negotiable. The position will initially run for 1 year, with an option to continue up to 3 years upon demonstration of excellent progress. Review of applications will begin June 1, 2022 and will continue until the position is filled.
Interested applicants should apply by attaching a cover letter that indicates fit and specific skills, Curriculum Vitae, contact information for three references, and two examples of scholarly writing, to Dr. Cheryl Wellington at the following address:
Cheryl Wellington, PhD
Professor and Vice Chair of Research
Pathology and Laboratory Medicine
Djavad Mowafaghian Centre for Brain Health
School of Biomedical Engineering
International Collaboration on Repair Discoveries
University of British Columbia
2215 Wesbrook Mall
Vancouver, British Columbia
Email: [email protected]
The Djavad Mowafaghian Centre for Brian Health at the University of British Columbia is located in Vancouver, Canada. The University of British Columbia is strongly committed to equity, diversity and inclusion and encourages applications from all qualified candidates including members of groups that have been marginalized on any ground enumerated under the BC Human Rights Code, including sex, sexual orientation, gender identity or expression, racialization, disability, political belief, religion, marital or family status, age, and/or status as a First Nation, Metis, Inuit or Indigenous person. Candidates who identify as being from any of these groups are encouraged to voluntarily self-identify in their application materials. All qualified candidates are encouraged to apply; however, priority will be given to Canadian citizens and permanent residents.