Research Fellow/Co-Curator of AntibioticDB
- University of Leeds
- Location: Leeds, United Kingdom
- Job Number: 7104371 (Ref #: FBSMB1228)
- Posting Date: Jul 1, 2022
Are you an ambitious researcher looking for your next challenge? Do you have an established knowledge of antibacterial chemotherapy and/or antibiotic discovery? Do you want to further your career in one of the UKs leading research-intensive Universities?
Applications are invited for a highly-motivated researcher to act as Co-Curator of AntibioticDB, a freely-accessible online database that was established in 2017 to capture detailed information regarding chemical compounds that have (or may possess) potential for use in antibacterial chemotherapy. An underpinning aim of AntibioticDB is to offer a mechanism by which discontinued compounds (i.e. those that failed to reach the clinic) might be re-investigated and potentially ‘rehabilitated’ to deliver new drug candidates into the ailing antibacterial development pipeline. This is a tantalising yet realistic prospect – the field has witnessed a number of instances where antibacterial compounds were initially discarded, but which were subsequently revisited and developed into successful antibacterial drugs (e.g. daptomycin, fidaxomicin).
AntibioticDB has already proven itself a valuable resource for researchers. However, at present it contains only a small proportion of known antibiotics, and would benefit from considerable expansion to better serve the user community and to realise maximum potential impact for antibacterial drug discovery efforts. This is the primary aim of the present project. Working alongside AntibioticDB curator Prof. Alex O’Neill, you would be responsible for mining the research and patent literature to identify additional compounds and information to add into AntibioticDB, in addition to providing continuous curation/ routine updating of the database.
You should have a PhD in molecular microbiology, biochemistry or a closely-allied discipline, along with extensive background knowledge of antibacterial chemotherapy and/ or antibiotic discovery, a proven ability to effectively interrogate the research and patent literature, and familiarity with basic concepts in database creation, maintenance and use.
This work will make a valuable contribution to the wider suite of activities underway in the O’Neill lab to help address the growing problem of antimicrobial resistance (AMR). This post is for 12 months with the possibility of further extension in the future.
To explore the post further or for any queries you may have regarding flexible working please contact:
|Location:||Leeds - Main Campus|
|Faculty/Service:||Faculty of Biological Sciences|
|School/Institute:||School of Molecular & Cellular Biology|
|Salary:||£34,304 to £40,927 p.a. pro rata|
|Working Time:||40% - We will consider flexible working arrangements|
|Post Type:||Part Time|
|Contract Type:||Fixed Term (for 12 months due to external funding)|
|Release Date:||Thursday 30 June 2022|
|Closing Date:||Sunday 10 July 2022|
The University community is made up of a wide range of people with diverse backgrounds and circumstances, which we value and regard as a great asset. As part of our continued commitment to equality and inclusion, we strive to create an environment where everyone can reach their full potential and have a real opportunity to participate in and contribute to our activities.