Postdoctoral Position in RNA-splicing and Systems Biology
- Yale University - Department of Therapeutic Radiology
- Location: New Haven, CT
- Job Number: 7107872
- Posting Date: Aug 11, 2022
- Application Deadline: Open Until Filled
Job DescriptionThe Robinson lab (Yale Cancer Center Department of Therapeutic Radiology) is seeking a computationally focused postdoctoral candidate with expertise in bioinformatic analysis including analysis and visualization of bulk RNA-seq and related whole genome assays (single cell RNA-seq, DNA mutation analysis, etc.) to join our translational research team.
Dr. Robinson is a physician scientist radiation oncologist who leads Yale’s inpatient radiation oncology consult service with clinical expertise in hematologic and central nervous system cancers. The lab has a translational focus with a goal to drive clinically-meaningful research to improve the treatment of patients with cancer through the lens of mRNA splicing diagnostics, prognostics, and therapeutics, particularly immune and cellular therapies. Work conducted in the lab has led to the identification of potential splicing-mediated mechanisms of resistance to CAR T-cell therapy in diffuse large B-cell lymphoma, in which Dr. Robinson has pioneered the use of bridging radiation therapy. Applicants with an interest in making a difference in cancer care are encouraged to apply.
Education, Qualifications and Skills:
-MD, PhD, or MD/PhD degrees
-Expertise/experience in bioinformatics, computational biology, computer science, mathematics, physics, or statistics
-Ability to work collaboratively with experimental postdoctoral fellows and scientists, computational biologists, graduate students, and other trainees in the laboratory.
-Prior experience in bulk genomic/transcriptomic analysis
-Expertise in basic data visualization
-Basic computational biology expertise
-Basic systems biology expertise
-Expertise in RNA-splicing
-Advanced computational biology skills including motif searching, machine learning, and high-dimensional data visualization skills
-Single-cell transcriptomic analysis
-Whole exome sequencing analysis
-Basic background in cancer biology
Interested candidates should email Timothy Robinson ([email protected] – note the “j”) and Amy Likens ([email protected]) with a CV, statement of interest and contact information for 2-3 references.
Yale University is an affirmative action/equal opportunity employer. Yale values diversity in its faculty, students, and staff and especially welcomes applications from women and underrepresented minorities.