- Baylor College of Medicine
- Location: Houston, TX
- Job Number: 7110872 (Ref #: 13150-en_US)
- Posting Date: Sep 17, 2022
- Application Deadline: Open Until Filled
The Ocular Surface laboratory in the Department of Ophthalmology at Baylor College of Medicine under direction of Cintia de Paiva, M.D., Ph.D. and Stephen Pflugfelder, M.D. is searching for a Post-doctoral Associate or Research Associate to study the cornea-trigeminal neural circuit in a recently funded project. The project investigates the effects of transient and/or prolonged corneal epithelial barrier disruption on nociceptor stimulation, corneal nerve density and RNA and epigenetic profiling in corneal cells and the trigeminal ganglion cells that project to the cornea. The benchmark accomplishments of this project will be a fundamental new understanding of the impact of corneal epithelial barrier disruption that occurs in common corneal diseases on the integrity and function of the corneal epithelial nerve network.
This project will utilize mouse models of corneal barrier disruption, as well as a range of experimental techniques including cell isolation, single cell RNA and ATAC-seq, in situ hybridization, and cornea and trigeminal immunostaining. The ideal candidate will have experience with some or all of these or similar methods. Candidates must have good communication skills and be willing to work with other lab members as a team. Expertise in the application and adaptation of numerous research techniques and procedures is also required.
- Plans, directs and conducts specialized and advanced research experiments.
- Evaluates and analyzes data.
- Establishes new research protocols and procedures.
- Summarizes research findings and publish results in research journals.
- Maintains laboratory operations.
- Supervises research staff.
- MD or Ph.D. in Basic Science, Health Science, or a related field.
- No experience required.
- Previous experience in cellular or molecular biology, or immunology research, either as a Ph.D. candidate or post-doctoral fellow.
- Proficiency with experimental design and analysis.
- Proficiency in performing basic molecular techniques such as tissue dissection, cell isolation and sorting, and immunostaining.
- Ability and willingness to work independently while also part of a dynamic research team.
- English writing skills.
- Authorization to work in the U.S.
- Experience with rodent care and animal husbandry, or willingness to be trained in animal handling and husbandry techniques is acceptable.
- Experience with basic cell and molecular biology techniques.
Baylor College of Medicine requires employees to be fully vaccinated -subject to approved exemptions-against vaccine-preventable diseases including, but not limited to, COVID-19 and influenza.
Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.
PD; CA; SN
Baylor College of Medicine fosters diversity among its students, trainees, faculty and staff as a prerequisite to accomplishing our institutional mission, and setting standards for excellence in training healthcare providers and biomedical scientists, promoting scientific innovation, and providing patient-centered care. - Diversity, respect, and inclusiveness create an environment that is conducive to academic excellence, and strengthens our institution by increasing talent, encouraging creativity, and ensuring a broader perspective. - Diversity helps position Baylor to reduce disparities in health and healthcare access and to better address the needs of the community we serve. - Baylor is committed to recruiting and retaining outstanding students, trainees, faculty and staff from diverse backgrounds by providing a welcoming, supportive learning environment for all members of the Baylor community.
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