Associate Research Scientist | Hematopoietic Stem Cell Aging

Trowbridge Lab

Bar Harbor, ME

The Trowbridge lab at The Jackson Laboratory is seeking an independent, highly motivated PhD-level scientist to lead a collaborative research program investigating the biological basis of hematopoietic stem cell aging and how this modifies risk of aging-associated diseases including cancer, cardiovascular disease, and Alzheimer’s disease. The Trowbridge lab studies hematopoietic stem cell aging, clonal hematopoiesis, and blood cancer development using a combination of approaches including engineered mouse models, in vivo and in vitro cellular assays, (epi)genomics assays, and cellular imaging (https://trowbridgelab.com)

The ideal candidate should have a strong training background in cell and molecular biology, genetics, the biology of aging, wet lab and computational experience, and prior expertise using in vivo mouse models. Through leading this program, this talented individual would have access to a world-class consortium of experts in aging and associated diseases as well as cancer biology through The Jackson Laboratory’s NCI-Designated Basic Research Cancer Center.

KEY RESPONSIBILITIES

• Following a training period, perform experiments and obtain data with minimal guidance; supervise junior staff to do the same
• Develop and optimize protocols
• Write manuscripts and grants, will be encouraged to obtain independent funding
• Execute and analyze independent research project(s) using efficient, flexible, and self-motivated work ethic
• Actively read scientific literature and develop new ideas for project direction(s)
• Organize and lead collaborative group projects internally and externally
• Contribute to ongoing projects within the lab by being an active team player
• Mentor and supervise incoming trainees and lab members as needed
• Prepare and give presentations on project(s) at research conferences and symposiums

QUALIFICATIONS

• Ph.D. in cell biology, molecular biology, genetics, or related field of study
• 3+ years of post-doctoral training
• Strong publication record in peer-reviewed journals
• Ability to integrate and apply feedback in a professional manner
• Exceptional organization and project management skills
• Demonstrated resourcefulness in finding appropriate solutions to problems and initiative in presenting alternatives and implementing solutions
• Experience using wet lab techniques, animal models and computational tools. Particularly desirable are experience in single cell transcriptomics, flow cytometry, histology and confocal microscopy, genetically diverse mouse models, genetic and genomic data analyses
• Excellent writing and communication skills, able to work independently and effectively with other members in a productive team

**Please submit your current CV and 1-page (maximum) statement of Research Interests and Career Goals at time of application. **

We are a diverse and inclusive research group, aspiring to produce top science and scientists through attentive and progressive mentoring and interdisciplinary teamwork.

About JAX:

The Jackson Laboratory (JAX) is an independent, nonprofit biomedical research institution with more than 2,400 employees. Headquartered in Bar Harbor, Maine, it has a National Cancer Institute-designated Cancer Center in Augusta, Maine, a genomic medicine institute in Farmington, Connecticut, and facilities in Ellsworth, Maine, Sacramento, California, and Shanghai, China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.

JAX employees work in a collaborative, value-driven, and team-based environment where the focus is on advancing science and improving patients’ lives. Researchers apply genetics to increase the understanding of human disease and advance treatments and cures for cancer, neurological and immune disorders, diabetes, aging, and heart disease. JAX was voted among the top 15 “Best Places to Work in Academia” in the United States in a poll conducted by The Scientist magazine!

EEO Statement:

The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.