Research Fellow in Structural Neuroscience and Cryo-electron Tomography
- University of Leeds
- Location: Leeds, United Kingdom
- Job Number: 7111707 (Ref #: FBSAC1007)
- Posting Date: Sep 27, 2022
Are you an ambitious researcher looking for the next exciting frontier in structural biology? Do you have an established background in cryoEM? Do you want to further your career at the cutting edge of in situ cryo-electron tomography and structural neuroscience at one of the UKs leading research intensive Universities?
We seek to appoint a Research Fellow to the research team led by Dr René Frank in the Astbury Centre and Faculty of Biological Sciences at the University of Leeds, Leeds, UK. The position is funded by the UKRI Future Leader Fellowship ‘Seeing inside the brain’ and is available for 3 years in the first instance. The successful applicant will undertake in situ structural studies of macromolecular complexes associated with brain synapses and Alzheimer’s disease in tissues and cells. The position will suit someone interested in cryo-electron tomography, Alzheimer’s disease and a desire to develop their careers in the rapidly expanding field of in situ structural biology.
You should have or be very close to completing a PhD in cryoEM, cryoET, bio-imaging and image analysis, or a closely allied discipline, with experience in computational image analysis and coding. A background in cryoEM (single particle analysis or cryoET), bio-imaging, neuroscience, computational image analysis, or a related discipline would be advantageous.
The Astbury Centre for Structural & Molecular Biology at the University of Leeds has excellent facilities for cryo-electron microscopy (two Titian Krios 300 kV equipped with Falcon-4 detectors and selectis-X energy filters), high-pressure freezer, cryo-fluorescence microscope, cryo-ultramicrotome, bioimaging (confocal and super-resolution microscopes) and access to FIB-SEM. The Astbury Centre is also well-equipped with instrumentation for biophysical analysis (e.g. AFM, mass photometry, fluorescence, multi-angle light scattering). Additionally, the University provides a state-of-the-art animal facility, high-throughput screening, mammalian genetics, chemical biology and proteomics.
The University of Leeds welcomes applications from anywhere in the world.
To explore the post further or for any queries you may have, please contact:
Dr René Frank, Group Leader and UKRI Future Leader Fellow
Email: [email protected]
|Location:||Leeds - Main Campus|
|Faculty/Service:||Faculty of Biological Sciences|
|Salary:||£35,333 to £42,155 p.a.|
|Working Time:||100% - this role will be based on the University campus, with scope for it to be undertaken in a hybrid manner. We are also open to discussing flexible working arrangements.|
|Post Type:||Full Time|
|Contract Type:||Fixed Term (for 3 years due to external funding)|
|Release Date:||Monday 26 September 2022|
|Closing Date:||Monday 24 October 2022|
The University community is made up of a wide range of people with diverse backgrounds and circumstances, which we value and regard as a great asset. As part of our continued commitment to equality and inclusion, we strive to create an environment where everyone can reach their full potential and have a real opportunity to participate in and contribute to our activities.