Project Scientist - Svendsen & Theodorescu Labs - Regenerative Medicine Institute & Cancer Program
- Cedars-Sinai Medical Center
- Location: Los Angeles, CA
- Job Number: 7115365 (Ref #: HRC0940947A)
- Posting Date: Nov 3, 2022
- Application Deadline: Open Until Filled
The Cedars-Sinai Medical Center is seeking a Project Scientist to join the laboratories of Dr. Dan Theodorescu and Dr. Clive Svendsen!
We are seeking a highly motivated Project Scientist to expand our iPSC modeling of BRCA1 cancers using fallopian tube organoid technology recently published in Cell Reports. We want now to generate more lines and learn how over-expression of “second hit” genes may accelerate tumor progression and lead to enhanced models of disease. Our laboratories have ongoing discovery projects directed at key molecules driving cancer growth, metastasis, and tumor microenvironment (TME, stroma/fibroblast) along with cutting edge iPSC and organoid technologies. Together we are using these systems to evaluate candidates for therapeutic targeting and clinical translation to trials in patients.
The successful candidate will be a driven, creative, team-oriented individual with a passion for helping to discover and move fundamental cancer biologic findings towards a clinical setting. The candidate will have a PhD or MD/PhD degree and background in stem cell tissue culture, functional genomics (including CRISPR, shRNA, and cDNA library use), and next-generation sequencing. A broad-based knowledge of stem cells, organoids, cancer biology, immunology, and signal transduction is an important characteristic of the successful applicant.
The Project Scientist works independently and in cooperation with the Principal Investigator to make significant and creative contributions to a research or creative project in any academic discipline. The Project Scientist may be an ongoing member of a research team or may be employed for a limited period of time to contribute high-level skills to a specific research or creative program. Project Scientists are not required to carry out independent research or to develop an independent research reputation and do not have teaching responsibilities. Ordinarily, the Project Scientist title will carry out research or creative programs as well as administration of day-to-day lab operations with supervision by a member of the Professorial Series.
Primary Job Duties and Responsibilities:
- May assist in preparation of grant proposals, submissions, publications and presentations but is not responsible for generating grant funds.
- May serve as PI for certain grants as approved by supervising member of the Professorial Series.
- May participate in publications and presentations as author or co-author.
- May develop, adapt and implement new research techniques and protocols.
- Assists in lab experiments.
- Analyzes, interprets, summarizes and compiles data.
- May lead or train Staff Research Associates and Research Fellows.
- Will assist in day-to-day laboratory activities.
- Appointees on an academic trajectory will be expected to commit a portion of their time to develop an independent range of research.
Doctorate (MD, PhD, VMD, or DDS) in the area directly related to the field of research specialization.
Experience and Skills:
- Completion of postdoctoral appointment in area of specialization, as applicable.
- Knowledge of PI’s area of research specialization.
- Demonstrated technical competency in a variety of research techniques and protocols.
- Scheduling flexibility including evening, weekend, and holiday rotation commitment may be necessary. Travel may be required.
- Function efficiently and cooperatively with a team of faculty, research associates, technicians, and students.
- Excellent written and oral communication skills are essential.
- Knowledge of safety standards and maintenance of specialized equipment.
Working Title:Project Scientist - Svendsen & Theodorescu Labs - Regenerative Medicine Institute & Cancer Program
Department:Regenerative Medicine Inst
Business Entity:Academic / Research
Job Specialty:Research Studies/Clinical Trials
Shift Length:8 hour shift
Cedars-Sinai is an EEO employer. Cedars-Sinai does not unlawfully discriminate on the basis of the race, religion, color, national origin, citizenship, ancestry, physical or mental disability, legally protected medical condition (cancer-related or genetic characteristics or any genetic information), marital status, sex, gender, sexual orientation, gender identity, gender expression, pregnancy, age (40 or older), military and/or veteran status or any other basis protected by federal or state law. If you need a reasonable accommodation for any part of the employment process, please contact us by email at [email protected] and let us know the nature of your request and your contact information. Requests for accommodation will be considered on a case-by-case basis. Please note that only inquiries concerning a request for reasonable accommodation will be responded to from this email address.
Cedars-Sinai will consider for employment qualified applicants with criminal histories, in accordance with the Los Angeles Fair Chance Initiative for Hiring.
At Cedars-Sinai, we are dedicated to the safety, health and wellbeing of our patients and employees. This includes protecting our patients from communicable diseases, such as influenza (flu) and COVID-19. For this reason, we require that all new employees receive a flu vaccine based on the seasonal availability of flu vaccine (typically during September through April each year) as a condition of employment, and annually thereafter as a condition of continued employment, subject to medical exemption or religious accommodation. For the same reason, you may also be required to receive other vaccines such as COVID-19 as a condition of employment. Cedars-Sinai reserves the right to make modifications to its required list of vaccines as required by law and/or policy.