Postdoctoral Fellow - Cellular Gene Therapy and Stem Cell Research
- City of Hope
- Location: Duarte, CA
- Job Number: 7136418 (Ref #: 10020541)
- Posting Date: 6 months ago
- Salary / Pay Rate: $31.00 - $34.23 / hour
- Application Deadline: Open Until Filled
Job Description
Join the forefront of groundbreaking research at the Beckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.
Dr. Angelo Cardoso is looking for a talented and highly motivated Postdoctoral Fellow to join the Laboratory for Cellular Medicine, Center for Gene Therapy. You will join a well-established group performing cutting-edge research, development and qualification of large-scale processes, and manufacture of products for gene therapy clinical trials, including first-in-human studies with genetically engineered hematopoietic stem and progenitor cells (HSPC) and T cells.
As a successful candidate, you will:
· Conduct research on next-generation targeted gene modification of human HSPC and iPSC, on strategies to modulate stemness and on the development of niche-mimetics.
· Interact with the Process Development team and will participate in the optimization of methods for efficient gene-modification of target cells and their transfer into clinical-scale manufacture processes, as well as in the development and qualification of project-specific potency and identity assays for release and characterization of these therapeutic products.
· You will be expected to perform high quality original research work, participate in the clinical translation of their work, prepare manuscripts for publication, contribute to extramural grant applications and the preparation of progress reports for funding agencies, and to submitrelevantpostdoctoralfellowship applications.
· PhD or MD in biological sciences with a strong interest in translational research. Preference will be given to candidates with expertise in the study of hematopoiesis and biology of HSPC, experimentation with primary human cells and iPSC, and gene editing and viral transduction.
· Expertise in cell selection, hematopoietic functional assays, multiparametric flow cytometry, PCR, and basic knowledge of molecular biology, are required.
· Excellent communication skills.
City of Hope is an equal opportunity employer. To learn more about our commitment to diversity, equity and inclusion, please click here
Salary / Pay Rate Information:
Pay Rate: $31.00 - $34.23 / hour
The estimated pay scale represents the typical [salary/hourly] range City of Hope reasonably expects to pay for this position, with offers determined based on several factors which may include, but not be limited to, the candidate’s experience, expertise, skills, education, job scope, training, internal equity, geography/market, etc. This pay scale is subject to change from time to time.
City of Hope is a community of people characterized by our diversity of thought, background and approach, but tied together by our commitment to care for and cure those with cancer and other life-threatening diseases. The innovation that our diversity produces in the areas of research, treatment, philanthropy and education has made us national leaders in this fight. Our unique and diverse workforce provides us the ability to understand our patients' needs, deliver compassionate care and continue the quest for a cure for life-threatening diseases. At City of Hope, diversity and inclusion is a core value at the heart of our mission. We strive to create an inclusive workplace environment that engages all of our employees and provides them with opportunities to develop and grow, both personally and professionally. Each day brings an opportunity to strengthen our work, leverage our different perspectives and improve our patients’ experiences by learning from others. Diversity and inclusion is about much more than policies and campaigns. It is an integral part of who we are as an institution, how we operate and how we see our future.
