Cedars-Sinai is a nonprofit academic healthcare organization serving the diverse Los Angeles community and beyond. We are one of the leading institutes for competitive research funding from the National Institutes of Health. As an international leader in biomedical research, we translate discoveries into successful treatments with global impact. Cedars-Sinai is a hub for biomedical research with discoveries occurring in 26 departments and institutes that encompass the full spectrum of medicine.

For more information on the Sergei Grivennikov Lab, please visit: https://www.cedars-sinai.edu/research/labs/grivennikov.html. Our lab is actively studying immunology, microbiota, tissue microenvironment and cancer using various animal models, organoids and a vast array of modern groundbreaking technologies. We work with models of intestinal inflammation, gastrointestinal cancers, effects of microbiota, inflammation and microbial metabolites on tissue inflammation and regeneration, as well as on cancer formation, progression and metastasis

Main research directions in the lab include:

1. Role of cytokine pathways and inflammation in inflammatory bowel disease and colon cancer
2. Role of functional microbiota in induction of inflammation, tumorigenesis and cancer metastasis
3. Role of Immune tumor microenvironment in progression of colon and pancreatic cancers.

Under general mentorship, the Administrative Research Associate III works closely with PI, providing technical and performing experiments at the intersection of immunology and cancer biology. The position is expected to be heavily involved into flow cytometry, cell sorting and other single cell based approaches for characterization of tumor microenvironment. May develop hypothesis and assist in planning steps for the investigative process. Coordinates all lab and/or clinical activities, including but not limited to, preparation of grant proposals, data analysis, multi-lab collaborations and creating independent presentations. Not responsible for generating grant funds.

Primary Duties and Responsibilities

• Provides miscellaneous research support (ad hoc data analysis, hypothesis development, programming, troubleshooting, etc.), including sample processing and cell isolation, flow cytometry and cell sorting, immunophenotyping of tumor microenvironment
• Analyzes data and prepares scientific findings for publication as author or co-author.
• May make independent presentations and drive multi-lab collaborations.
• May provide system administration and maintenance for the local workstation network.
• Leads and trains Research Lab Assistants, Research Fellow, lower level Research Associates, and other related support staff and may be requested by PI to take on specific supervisory activities.
• Orients new Research Fellows and/or Research Scientists to day-to-day lab operations and procedures.
• Monitors and ensures compliance with safety standards and procedures

Requirements: 

• Bachelor of Science Degree or above
• 4 years of Research laboratory experience, required, including experience with immunology and/or cancer biology
• 2 years of experience in a research specialty, preferred. Experience with multicolor flow cytometry and data analysis is preferrable.

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