Postdoctoral Associate

Bloss & Howell Labs

Bar Harbor, Maine

Investigating the role of genetic risk factors for Alzheimer’s disease on neural circuit dysfunction

The labs of Drs. Gareth Howell and Erik Bloss at The Jackson Laboratory in Bar Harbor Maine are seeking a postdoctoral fellow to investigate the role of genetic risk factors for Alzheimer’s disease (AD) on synaptic plasticity and neural circuit dysfunction. The Howell lab utilizes genetic and multi-omic approaches to study neurodegenerative diseases including AD and related dementias (ADRDs). Of relevance to this position, Dr. Howell is one of the lead PIs on MODEL-AD (Model Organism Development and Evaluation of late-onset AD), an NIA-funded consortium charged with developing improved mouse models of LOAD. The Bloss lab leverages high resolution imaging, observation and manipulation of in vivo neural activity, and genetic perturbations in specific neurons, to define how neural circuits function in health and disease. This position will benefit from joint mentoring from Drs. Howell and Bloss, as well the resources being generated by MODEL-AD.

The ideal candidate will have a PhD in Neuroscience, Genetics or a related discipline, a willingness to work in a team environment and a passion for understanding the relationship between genetic risk factors and neural circuit dysfunction in AD. Previous experience in mouse handling, surgical techniques, and bioinformatics is preferred but not essential.

For more information contact gareth.howell@jax.org or erik.bloss@jax.org

JAX Salary
Year 0 - 1 $65,589
Year 1 - 2 $67,318
Year 2 - 3 $69,095
Year 3 - 4 $70,521
Year 4 - 5 $72,877
Year 5 - 6 $75,569

About JAX:

The Jackson Laboratory is an independent, nonprofit biomedical research institution with a National Cancer Institute-designated Cancer Center and nearly 3,000 employees in locations across the United States (Maine, Connecticut, California),Japan andChina. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.

Founded in 1929, JAX applies over nine decades of expertise in genetics to increase understanding of human disease, advancing treatments and cures for cancer, neurological and immune disorders, diabetes, aging and heart disease. It models and interprets genomic complexity, integrates basic research with clinical application, educates current and future scientists, and provides critical data, tools and services to the global biomedical community. For more information, please visitwww.jax.org​​​​​​​.

EEO Statement:

The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.