Postdoctoral Associate | Tumor Project

Paust Lab

Farmington, CT

A post-doctoral position is available in the laboratory of Dr. Silke Paust on or after September 1st, 2023.

The research projects will focus on NK cell responses to malignancy using mice, humanized mice, and human specimens.

The project seeks to develop NK cell-based immunotherapies to prevent or cure solid tumors. This work will be performed using genetically engineered lung cancer mouse models and in-house generated patient-derived xenograft models (lung, and pancreatic cancer).

The successful candidate must be able to work independently, as well as in a team environment, pay close attention to detail and adhere to deadlines regularly. Excellent communication and interpersonal skills are essential. He/she/they will be detail-oriented, self-motivated, a fast learner, and possess excellent time management, organizational, written, and verbal communication skills. The ability to take direction and use independent judgment to meet experimental goals and deadlines is required. The successful candidate must be able to independently develop experimental protocols and approaches to troubleshooting experimental protocols, and perform advanced planning of experiment setups, data collection, and results for analysis. A strong commitment to experimental goals, career goals, and deadlines is required. Therefore, willingness to work into the evening and occasional weekend work is absolutely required. Prior post-doctoral experience is not required for this position.

Required Qualifications:

• PhD in immunology, cancer biology, or a related life science field, or a DVM or a related degree.
• Advanced immunology and NK cell biology expertise
• Experience with mouse models of disease (PDX, mouse tumor models)
• Experience with multiparameter/digital flow cytometry and data analysis
• Sterile tissue culture and in vitro assays (quantitative PCR, NK cell based killing and proliferation assays, etc.)
• Standard molecular biology and biochemical techniques, including microscopy
• Omics, bioinformatics, and biostatistics expertise strongly preferred
• At least 1 year of BSL-2 laboratory techniques and BSL-2 animal model experience

Positions require successful completion of required training courses, i.e. animal use, BL-2 safety, and general lab and chemical safety training.

Years of Postdoc Experience
0-1 $57,034 – 61,397
1-2 $58,537 – 63,015
2-3 $60,083 – 64,679
3-4 $61,323 – 66,014
4-5 $63,371 – 68,219
5 $65,712 – 70,739

About JAX:

The Jackson Laboratory is an independent, nonprofit biomedical research institution with a National Cancer Institute-designated Cancer Center and nearly 3,000 employees in locations across the United States (Maine, Connecticut, California),Japan andChina. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.

Founded in 1929, JAX applies over nine decades of expertise in genetics to increase understanding of human disease, advancing treatments and cures for cancer, neurological and immune disorders, diabetes, aging and heart disease. It models and interprets genomic complexity, integrates basic research with clinical application, educates current and future scientists, and provides critical data, tools and services to the global biomedical community. For more information, please visitwww.jax.org​​​​​​​.

EEO Statement:

The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.