Summary

Our lab focuses on studying the functional and clinical impact of poor prognosis tyrosine kinase aberrations identified from cancer genome sequencing. We use a variety of preclinical models including cancer cell lines, Organoid cultures, patient-derived xenografts (PDXs), and Genetically engineered mouse models (GEMM). Our team made significant contributions on translating genome-sequencing findings into successful phase II clinical trials. (Bose. R and Kavuri. SM, Cancer Discovery, 2013; Kavuri. SM et al, Cancer Discovery, 2015; Ben-Baruch NE. et al, JNCCN, 2015; Ma. C et al, 2017, CCR; Huang. Kl.et al, Nature Communication, 2017, Punturi. N. et. al, Nature Communication, 2021, and Kalra. R. et. al, Cancer Research, 2022). We are seeking highly motivated postdoctoral candidates, who are interested in translational solid tumor research. 
 

Interested individuals should send a cover letter, CV, and the names/phone numbers of three people who could provide letters of reference by email to MeghaShyam.Kavuri@bcm.edu

Job Duties

• Prepares and conducts laboratory research experiments.
• Collects, compiles and analyzes data.
• Conducts literature searches and summarizes information in an appropriate format for a particular study.
• Documents results of experiments.
• Selects, evaluates and applies techniques used in routine research.
• Seeks external funding via grants applications/submissions.
• Engages in teaching graduate or medical students.
• Involves in departmental committee duties.
• Trains and supervises less experienced research staff such as graduate students and postdocs.
• Collaborates with scientists out of the lab for multidisciplinary study.
• Develops new model and technique to support the cancer-related research in the lab.
•  Advises junior scientists and provide guidance on their projects.
• Serves as the animal ambassador to train all the lab members on aseptic surgical procedures.

Minimum Qualifications

• MD or Ph.D. in Basic Science, Health Science, or a related field.
• No experience required.

Preferred Qualifications

• The successful applicant must have PhD and/or MD and have strong skills with handling animal models including performing/maintaining therapeutic experiments using PDX models.
• Additionally, applicant must have hands on experience with genotyping of GEMM models.
• Bioinformatics skills will be advantageous.
• The applicant should have published in top tier journals and have successfully completed projects independently.
• Candidates who have recently complete or are about to complete their PhD will be considered.
• The candidates are expected to establish independent research projects and to generate high impact publications, which should provide the postdoctoral fellows with an excellent opportunity for further career development in academia.