Post Doc Fellow, Division of Hematology and Oncology
- the University of Cincinnati
- Location: Cincinnati, OH
- Job Number: 7223327
- Posting Date: Feb 29, 2024
Job Description
Post Doc Fellow, Division of Hematology and Oncology
Founded in 1819, the University of Cincinnati ranks among the nation’s best urban public research universities. Home to over 50,000 students, 11,000 faculty and staff and 332,000 alumni, UC combines a Top 35 public research university with a physical setting The New York Times calls “the most ambitious campus design program in the country.”
With the launch of Next Lives Here, the Cincinnati Innovation District, a $100 million JobsOhio investment, nine straight years of record enrollment, global leadership in cooperative education, a dynamic academic health center and entry into the Big 12 Conference, UC’s momentum has never been stronger. UC’s annual budget tops $1.65 billion and its endowment totals $1.8 billion.
Job Overview
As one of the oldest medical schools in the country, the University of Cincinnati College of Medicine (COM) has a reputation for training best-in-class health care professionals and developing cutting-edge procedures and research that improves the health and clinical care of patients. In partnership with the UC Health academic healthcare system and Cincinnati Children’s Hospital Medical Center, College of Medicine’s doctors are transforming the world of medicine every day. The Division of Hematology and Oncology is a top-tier department with world-renowned faculty and staff. With world-class research, teaching and medical practice opportunities, why not choose the University of Cincinnati College of Medicine?
Dr. Vladimir Bogdanov is recruiting a Post Doctoral Fellow to work in his lab focusing on alternatively spliced Tissue Factor (asTF) as a potential therapeutic target in gastrointestinal malignancies. Alternatively spliced Tissue Factor (asTF) is a soluble form of Tissue Factor (TF), the trigger of blood clotting. We were the first to report that asTF is elevated in the cancer lesions and circulating blood of patients suffering from pancreatic ductal adenocarcinoma, and hepatocellular carcinoma. Mechanistically, asTF protein acts as a cell agonist promoting growth and spread of malignant cells; our recently developed inhibitory antibody against asTF is currently being tested in animal models. Areas of interest include, but not limited to, the consequences of antibody-mediated inhibition of asTF on primary and metastatic tumor growth; the mechanisms regulating asTF biosynthesis in malignant cells; and the potential utility of asTF as a biomarker of disease aggressiveness and/or recurrence.
Essential Functions
• Learn to rapidly translate new discoveries into patient care.
• Provide formal and integrated instruction on the role of intellectual property protection in drug development in the context of a complex economy that is both market-based, and government-regulated.
• Provide comprehensive didactic and practical training in anti-cancer compound evaluation, with a primary focus how to conceptualize, design, manage, and successfully carry to completion a clinical trial involving a new therapeutic agent.
• Foster a collaborative structure that fosters creative and productive interactions between PhD scientists and MD-MD/PhD clinicians.
Minimum Requirements
MD, MD/PhD, PhD, ScD, or equivalent degree in medicine/biomedical sciences or a related field.
Required Experience
• In-depth knowledge of specialized field, process or discipline.
• May require experience with specialized software programs.
Physical Requirements/Work Environment
• Office environment/no specific unusual physical or environmental demands.
Compensation and Benefits
UC offers a wide array of complementary and affordable benefit options, to meet the financial, educational, health, and wellness needs of you and your family. Eligibility varies by position and FTE.
• Competitive salary range dependent on the candidate's experience.
• Comprehensive insurance plans including medical, dental, vision, and prescription coverage.
• Flexible spending accounts and an award-winning employee wellness program, plus an employee assistance program.
• Financial security via our life and long-term disability insurance, accident and illness insurance, and retirement savings plans.
• Generous paid time off work options including vacation, sick leave, annual holidays, and winter season days in addition to paid parental leave.
• Tuition remission is available for employees and their eligible dependents.
• Enjoy discounts for on and off-campus activities and services.
If interested, please apply online at https://bit.ly/49vtg9t
As a UC employee, and an employee of an Ohio public institution, if hired you will not contribute to the federal Social Security system, other than contributions to Medicare. Instead, UC employees have the option to contribute to a state retirement plan (OPERS, STRS) or an alternative retirement plan (ARP).
To learn more about why UC is a great place to work, please visit our careers page at https://www.uc.edu/careers.html.
For questions about the UC recruiting process or to request accommodations with the application, please contact Human Resources at [email protected].
The University of Cincinnati, as a multi-national and culturally diverse university, is committed to providing an inclusive, equitable and diverse place of learning and employment. As part of a complete job application you will be asked to include a Contribution to Diversity and Inclusion statement.
The University of Cincinnati is an Equal Opportunity Employer.
Founded in 1819, the University of Cincinnati ranks among the nation’s best urban public research universities. Home to over 50,000 students, 11,000 faculty and staff and 332,000 alumni, UC combines a Top 35 public research university with a physical setting The New York Times calls “the most ambitious campus design program in the country.”
With the launch of Next Lives Here, the Cincinnati Innovation District, a $100 million JobsOhio investment, nine straight years of record enrollment, global leadership in cooperative education, a dynamic academic health center and entry into the Big 12 Conference, UC’s momentum has never been stronger. UC’s annual budget tops $1.65 billion and its endowment totals $1.8 billion.
Job Overview
As one of the oldest medical schools in the country, the University of Cincinnati College of Medicine (COM) has a reputation for training best-in-class health care professionals and developing cutting-edge procedures and research that improves the health and clinical care of patients. In partnership with the UC Health academic healthcare system and Cincinnati Children’s Hospital Medical Center, College of Medicine’s doctors are transforming the world of medicine every day. The Division of Hematology and Oncology is a top-tier department with world-renowned faculty and staff. With world-class research, teaching and medical practice opportunities, why not choose the University of Cincinnati College of Medicine?
Dr. Vladimir Bogdanov is recruiting a Post Doctoral Fellow to work in his lab focusing on alternatively spliced Tissue Factor (asTF) as a potential therapeutic target in gastrointestinal malignancies. Alternatively spliced Tissue Factor (asTF) is a soluble form of Tissue Factor (TF), the trigger of blood clotting. We were the first to report that asTF is elevated in the cancer lesions and circulating blood of patients suffering from pancreatic ductal adenocarcinoma, and hepatocellular carcinoma. Mechanistically, asTF protein acts as a cell agonist promoting growth and spread of malignant cells; our recently developed inhibitory antibody against asTF is currently being tested in animal models. Areas of interest include, but not limited to, the consequences of antibody-mediated inhibition of asTF on primary and metastatic tumor growth; the mechanisms regulating asTF biosynthesis in malignant cells; and the potential utility of asTF as a biomarker of disease aggressiveness and/or recurrence.
Essential Functions
• Learn to rapidly translate new discoveries into patient care.
• Provide formal and integrated instruction on the role of intellectual property protection in drug development in the context of a complex economy that is both market-based, and government-regulated.
• Provide comprehensive didactic and practical training in anti-cancer compound evaluation, with a primary focus how to conceptualize, design, manage, and successfully carry to completion a clinical trial involving a new therapeutic agent.
• Foster a collaborative structure that fosters creative and productive interactions between PhD scientists and MD-MD/PhD clinicians.
Minimum Requirements
MD, MD/PhD, PhD, ScD, or equivalent degree in medicine/biomedical sciences or a related field.
Required Experience
• In-depth knowledge of specialized field, process or discipline.
• May require experience with specialized software programs.
Physical Requirements/Work Environment
• Office environment/no specific unusual physical or environmental demands.
Compensation and Benefits
UC offers a wide array of complementary and affordable benefit options, to meet the financial, educational, health, and wellness needs of you and your family. Eligibility varies by position and FTE.
• Competitive salary range dependent on the candidate's experience.
• Comprehensive insurance plans including medical, dental, vision, and prescription coverage.
• Flexible spending accounts and an award-winning employee wellness program, plus an employee assistance program.
• Financial security via our life and long-term disability insurance, accident and illness insurance, and retirement savings plans.
• Generous paid time off work options including vacation, sick leave, annual holidays, and winter season days in addition to paid parental leave.
• Tuition remission is available for employees and their eligible dependents.
• Enjoy discounts for on and off-campus activities and services.
If interested, please apply online at https://bit.ly/49vtg9t
As a UC employee, and an employee of an Ohio public institution, if hired you will not contribute to the federal Social Security system, other than contributions to Medicare. Instead, UC employees have the option to contribute to a state retirement plan (OPERS, STRS) or an alternative retirement plan (ARP).
To learn more about why UC is a great place to work, please visit our careers page at https://www.uc.edu/careers.html.
For questions about the UC recruiting process or to request accommodations with the application, please contact Human Resources at [email protected].
The University of Cincinnati, as a multi-national and culturally diverse university, is committed to providing an inclusive, equitable and diverse place of learning and employment. As part of a complete job application you will be asked to include a Contribution to Diversity and Inclusion statement.
The University of Cincinnati is an Equal Opportunity Employer.
