Postdoctoral Associate
- Baylor College of Medicine
- Location: Houston, TX
- Job Number: 7255160 (Ref #: 19728-en_US)
- Posting Date: Jun 14, 2024
Job Description
Summary
This position will develop small animal models for cardiac diseases to help develop novel therapies for heart diseases. The postdoctoral fellow will perform small animal survival surgeries to produce cardiovascular disease models. He/she is expected to be able to execute the experiment, collect tissue samples at the end of the experiment, perform analysis and report the result. The end experiments will include multiomics analysis, such as bulk RNA and scRNAseq, metabolomics and proteomics analysis.
Job Duties
- Plans and executes experiment.
- Analyzes and presents data.
- Writes manuscript and oral presentation.
- Plans animal experiment.
- Performs surgery and pre-post- surgical care.
- Coordinates with various core facility for data collection.
- Procures tissue sample and performs final molecular and histological experiments and analysis.
- Sets up animal cohorts for experiment and performs pre and post surgical care and daily injection of testing compounds.
- Performs tissue sample procurement at the end of the survival experiment, as well as genotyping, basic molecular biology, histology, immunohistochemistry experiments.
- Performs cardiovascular survival surgeries, including transaortic constriction, myocardial infarction and ischemia referfusion.
- Performs primary cell isolation and culture for cardiovascular cell types.
- Performs data analysis of scRNAseq and other omics.
- Summarizes data and report.
Minimum Qualifications
- MD or Ph.D. in Basic Science, Health Science, or a related field.
- No experience required.
Preferred Qualifications
- Recent (1-3 year) of MD or PhD graduate with experience in cardiovascular animal research.
- Surgical skills are greatly appreciated.
- Bioinformatics skills are greatly appreciated.
- Experience with iPSC-cardiomyocytes or organoid is a plus.
Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.
Baylor College of Medicine fosters diversity among its students, trainees, faculty and staff as a prerequisite to accomplishing our institutional mission, and setting standards for excellence in training healthcare providers and biomedical scientists, promoting scientific innovation, and providing patient-centered care. - Diversity, respect, and inclusiveness create an environment that is conducive to academic excellence, and strengthens our institution by increasing talent, encouraging creativity, and ensuring a broader perspective. - Diversity helps position Baylor to reduce disparities in health and healthcare access and to better address the needs of the community we serve. - Baylor is committed to recruiting and retaining outstanding students, trainees, faculty and staff from diverse backgrounds by providing a welcoming, supportive learning environment for all members of the Baylor community.