Area of research: The Lab is developing novel therapies by reprogramming the tumor microenvironment. The emphasis is on identifying secreted factors by mammary fibroblasts that induce tumor suppression and recruit immune cells. This is an NCI-funded program with opportunities to innovate. The Lab is equipped with state-of-the-art instruments, 3D imaging systems, and a high-end computing server and closely interacts with the Proteomics and Animal Core facilities at the University of Nevada, Reno.

Responsibilities are:
• Design and implement experiments for investigating the mechanism of tumor suppression in Patient-Derived organoids and PDXs,
• Perform validation studies in the mouse models,
• Investigate the mechanism by which cancer-associated fibroblasts can be reprogrammed,
• Work closely with the PI and his Graduate students in all experimental designs,
• Participate and present at NCI-sponsored meetings and work closely with the PI in manuscript preparation and
• Develop a K99 proposal (pathway to independence) supporting your career.

Required Skills are proficiency in
• Cell biology and 3D organoid cultures
• Immunostaining and microscopy
• Basic techniques in cell and molecular biology such as transfection, transduction, immunostaining, microscopy, and western blotting
• Preparing tumor histology sections collected from animal models
• “Rigorous” experimental design and validation.

Please send your CV to [email protected] with the subject heading “Prospective Postdoctoral fellow.”