The Chaitali Ghosh lab in the Department of Biomedical Engineering, Lerner Research Institute at Cleveland Clinic, Cleveland, OH is recruiting an enthusiastic and motivated postdoctoral research fellow to join on a project focusing on the Molecular Mechanism of Glucocorticoid Receptor, Cytochrome P450, and P-Glycoprotein Axis on Drug Regulation at the Blood-Brain Barrier in Epilepsy. The Ghosh laboratory is engaging in multi-disciplinary research projects in blood-brain barrier and epilepsy research by collaborating with basic and clinical researchers from Lerner Research Institute and the Neurological Institutes at Cleveland Clinic.

A successful postdoctoral candidate should have a PhD in the relevant field with a strong background in basic science, molecular biology, blood-brain barrier research, rodent seizure/epilepsy models and neuroscience. The candidate should be well-versed with basic neurobiology, molecular biology, cell culture techniques, rodent electrode implantation surgery and recording of brain activity. Applicant should be able to demonstrate a commitment to research, a collaborative work ethic and strong communication skills, both written and verbal. Highly motivated individuals with a PhD or MD/PhD in relevant area are encouraged to apply. Job Responsibilities includes independent project design with the goal of data generation, analysis, interpretation and manuscript preparation; perform experiments and make new discoveries; present data for manuscripts and conferences; procure independent funding to support research and train junior personnel.

Principal Investigator: Chaitali Ghosh, PhD

Lerner Research Institute Department: Biomedical Engineering

Lab Research Topics:

• Blood-brain barrier
• Epilepsy and epilepsy with other comorbidities
• Cellular and Molecular Neurobiology
• Pharmacokinetics and Pharmacodynamics
• Epigenetics and biomarkers
• For more information about the lab’s research, please visit: https://www.lerner.ccf.org/biomedical-engineering/ghosh/ or contact Dr. Chaitali Ghosh at [email protected].

Job Responsibilities:

• Independent project design with the goal of data generation, analysis, interpretation and manuscript preparation
• Perform experiments independently
• Ability to design projects, generate, analyse and intergrate data for presentations and manuscript
• Procure independent funding to support research
• Rodent brain surgeries, electrode implantation & recording

Education:

• PhD or MD/PhD required
• MD with relevant laboratory experience may substitute for PhD

Languages:

• English Proficiency proof required for candidates arriving on J-1, J-2, or F1 + OPT visa status

Work Experience:

• Previous experience in a research or academic setting. Graduate student experience meets this requirement.
• Scientific writing experience

Additional Preferred Qualities:

• Passionate towards research and new discoveries
• Good communication skills and hardworking ethics
• Collegial and excellent team player
• Demonstrate good scientific writing skills and knowledge in basic research
• Ability to operate lab equipment's and computer software's for analysis

Physical Requirements:

• Ability to perform work in a stationary position for extended periods
• Ability to operate a computer and other office equipment
• Ability to communicate and exchange accurate information
• Ability to distinguish color
• Manual dexterity to handle specimens and repair equipment
• Ability to lift and transport equipment or specimens weighing up to 20 pounds
• May be exposed to hazardous chemicals, bio-hazards, radioactive materials, etc.

Personal Protective Equipment:

• PPE per institutional requirements; may vary by laboratory

Preferred Application Materials:

• CV or NIH format Biosketch,
• Statement of research accomplishments (1-page)
• Names of 3 Referees
• All application materials should be submitted directly via email to Chaitali Ghosh at [email protected].

Keywords: Postdoc, Research, LRI, Lerner Research Institute, Research fellow, Cleveland Clinic, In vitro and In vivo Blood-brain barrier models, Rodent Brain surgery, Epilepsy Research, Blood-brain barrier Research, Rat and mouse models, Immunohistochemistry, Western Blotting, High Performance Liquid Chromatography/Mass Spectrometry, RT-PCR, Epigenetic, DNA methylation, ELISA, Primary cell cultures, Neurovascular Unit, Molecular Neurobiology, Biomarkers