Postdoctoral Associate - Drug metabolism and toxicity
- Baylor College of Medicine
- Location: Houston, TX
- Job Number: 7368532 (Ref #: 25976-en_US)
- Posting Date: Newly posted
Job Description
Summary
The Center for Drug Discovery ( https://www.bcm.edu/research/centers/drug-discovery) is a strategic research center at Baylor College of Medicine in Houston, Texas. The lab is looking for self-motivated candidates with a strong sense of teamwork, curiosity, and enthusiasm for biomedical research (specifically, drug metabolism and blood testis barrier). The lab is well-equipped with Thermos UHPLC-Q Exactive MS, Orbitrap Exploris™ 120, Thermo Quintus (triple quadruple), and Imaging mass spectrometry (IMS, Bruker timsTOF fleX MALDI-2). Understanding the drug metabolism could predict the possible adverse events of drugs in clinic and also could reduce the risk of the drug candidates in drug development. Determining chemical features passing BTB will facilitate the drug development for therapeutic targets behind BTB. Strong scientific judgment, critical thinking, and the ability to identify important scientific questions will be highly valued.
Job Duties
- Plans, designs and conducts animal experiments as well as cell cultures.
- Characterizes the drug metabolites using High-resolution LC-MS and NMR.
- Analyzes LC-MS data from mouse tissue and plasma to evaluate their abilities for passing through BTB using imaging mass spectrometry.
- Documents and interprets experimental results and reports to principal investigators.
- Assists with manuscript preparation and writing.
- Conducts literature searches and summarizes information in an appropriate format for a particular study.
- Performs other job related duties as assigned.
Minimum Qualifications
- MD or Ph.D. in Basic Science, Health Science, or a related field.
- No experience required.
Preferred Qualifications
- Experience in LC-MS-based omics and imaging mass spectrometry method development and sample preparation, and data analysis.
- Has strong academic integrity, independent research ability, and a collaborative team spirit.
Baylor College of Medicine fosters diversity among its students, trainees, faculty and staff as a prerequisite to accomplishing our institutional mission, and setting standards for excellence in training healthcare providers and biomedical scientists, promoting scientific innovation, and providing patient-centered care. - Diversity, respect, and inclusiveness create an environment that is conducive to academic excellence, and strengthens our institution by increasing talent, encouraging creativity, and ensuring a broader perspective. - Diversity helps position Baylor to reduce disparities in health and healthcare access and to better address the needs of the community we serve. - Baylor is committed to recruiting and retaining outstanding students, trainees, faculty and staff from diverse backgrounds by providing a welcoming, supportive learning environment for all members of the Baylor community.
